Reinforcement signalling in Drosophila; dopamine does it all after all

What does it all mean?

Cell signalling - the proteomics of it all.

A challenge for biomedical scientists today is to arrive at an understanding of cellular behavior on a global scale. The advent of DNA microarrays has greatly facilitated discovery of gene expression profiles associated with different cellular states. The problem of understanding cellular signaling at the level of the interacting proteins is in some ways more challenging. Ashman et al. discuss ...

Is it tonotopy after all?

In this functional MRI study the frequency-dependent localization of acoustically evoked BOLD responses within the human auditory cortex was investigated. A blocked design was employed, consisting of periods of tonal stimulation (random frequency modulations with center frequencies 0.25, 0.5, 4.0, and 8.0 kHz) and resting periods during which only the ambient scanner noise was audible. Multiple...

Finding A Vendor Who Does It All

56 Waste Alternatives / Waste-to-Energy of the town’s wastes are burned in antiquated incinerators, but these lack pollution controls and are subject to continual breakdowns. Huntington can’t look to neighboring communities for help; most of those communities have similar problems. When looking for a solution to its disposal situation, Huntington N. El’s integrated approach to solid waste manag...

What does it all mean to you?

Nearly 20 years ago, I introduced a special series of articles for Trends in Neurosciences (5:295, 1982) that sought to illustrate some of the then-latest developments in molecular neuroscience. That was the time when neuroscientists were beginning to borrow heavily from the nascent field of molecular genetics, just as we had previously borrowed flagrantly from the previously powerful fields of...